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RESETTNG THE IMMUNE SYSTEM  TO  TREAT
AUTOIMMUNE,  CHRONIC   INFLAMMATORY   DISEASE
AND  CANCER

ABOUT SFA THERAPEUTICS

SFA Therapeutics is a clinical-stage biopharmaceutical company committed to developing disease-modifying therapies that restore healthy immune system function in patients with cancer, inflammatory and autoimmune disease.​

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Our first-in-class Treg modulators target a fundamental cause of immune dysregulation to restore durable immune homeostasis across autoimmune disorders. We discovered ways to manipulate the molecular structure and develop         oral delivery formulations, increasing the selectivity and specificity of our                          small- molecule compounds after elucidating pathways and targets.  ​​​​

 

 

 

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​We have developed this platform technology by in-depth study of the natural regulators of the immune system present in the gut microbiome which allows us to safely target specific diseases and create disease-specific drugs.  

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​Join us on this exciting journey as we work towards a healthier future, one molecule at a time.

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INNOVATIVE  DRUGS 

PREDICTABLE OUTCOMES

Innovative Oral   Formulations Allow for Consistent Clinical Outcomes

PATHWAY TARGETED

Small Molecules that Interact Selectively with Disease-specific Targets and Maintain Immune Homeostasis  

SUPERIOR 
SAFETY

Small Molecules that Mimic Endogenous Substances found in the Human Body
 

HIGHLY EFFICACIOUS

Boosts Anti-inlammatory IL-10 Expression and Downregulates Pro-inflammatory Cytokines

LOW COST

Seamless Manufacturing Process 

 POWERFUL  and  NOVEL  PLATFORM

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TARGETED BIOSYNTHESIS

PLATFORM

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AUTOIMMUNE DISEASES

PSORIASIS, RHEUMATOID ARTHRITIS,

UVEITIS AND BULLOUS PEMPHIGOID

CANCERS

HEPATOCELLULAR CARCINOMA, PANCREATIC CANCER AND MYELOID LEUKEMIAS

INFECTIOUS DISEASES

POST-VIRAL INFLAMMATORY COMPLICATIONS​

LIVER DISEASES

FIBROSIS AND MASH/NASH â€‹

ANTI-INFLAMMATORY ADJUVANTS

CAR-T THERAPIES

OUR PARTNERS

SFA THERAPEUTICS
IS  A

VENTURE  CAPITAL  BACKED  CLINICAL-STAGE  BIOTECHNOLOGY COMPANY

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SFA  THERAPEUTICS  IN  THE  NEWS

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JENKINTOWN, Pa., August 10, 2025 PR NEWSWIRE --The Galien Foundation Announces SFA Therapeutics as a 2025 Prix Galien USA Nominee for Best Startup

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JENKINTOWN, Pa., May12, 2025 BIONJ -

SFA Therapeutics Awarded Most Innovative Company at BIONJ Liberty Center Partnering Conference

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JENKINTOWN, Pa., March 13, 2025  BioWorld -- First-in-class oral immunomodulator shows efficacy in psoriasis models​

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JENKINTOWN, PA., March 13, 2025 --Technical.ly This pharma startup backed by Y Combinator aims to treat multiple diseases, for good

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JENKINTOWN, Pa., March 7, 2025 BUSINESS WIRE -- SFA Therapeutics Announces Positive Phase 1b Data of SFA-002 in Mild-to-Moderate Psoriasis

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