

TM


RESETTNG THE IMMUNE SYSTEM TO TREAT
AUTOIMMUNE, CHRONIC INFLAMMATORY DISEASE
AND CANCER
ABOUT SFA THERAPEUTICS
SFA Therapeutics is a clinical-stage biopharmaceutical company committed to developing disease-modifying therapies that restore healthy immune system function in patients with cancer, inflammatory and autoimmune disease.​
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Our first-in-class Treg modulators target a fundamental cause of immune dysregulation to restore durable immune homeostasis across autoimmune disorders. We discovered ways to manipulate the molecular structure and develop oral delivery formulations, increasing the selectivity and specificity of our small- molecule compounds after elucidating pathways and targets. ​​​​
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​We have developed this platform technology by in-depth study of the natural regulators of the immune system present in the gut microbiome which allows us to safely target specific diseases and create disease-specific drugs.
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​Join us on this exciting journey as we work towards a healthier future, one molecule at a time.



INNOVATIVE DRUGS
PREDICTABLE OUTCOMES
Innovative Oral Formulations Allow for Consistent Clinical Outcomes
PATHWAY TARGETED
Small Molecules that Interact Selectively with Disease-specific Targets and Maintain Immune Homeostasis
SUPERIOR
SAFETY
Small Molecules that Mimic Endogenous Substances found in the Human Body
HIGHLY EFFICACIOUS
Boosts Anti-inlammatory IL-10 Expression and Downregulates Pro-inflammatory Cytokines
LOW COST
Seamless Manufacturing Process
POWERFUL and NOVEL PLATFORM
![102158395_eps_normal_none [Converted].png](https://static.wixstatic.com/media/abea01_08ad758a19dd4b5f976a8010220e7a2d~mv2.png/v1/fill/w_477,h_570,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/102158395_eps_normal_none%20%5BConverted%5D.png)
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TARGETED BIOSYNTHESIS
PLATFORM

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AUTOIMMUNE DISEASES
PSORIASIS, RHEUMATOID ARTHRITIS,
UVEITIS AND BULLOUS PEMPHIGOID
CANCERS
HEPATOCELLULAR CARCINOMA, PANCREATIC CANCER AND MYELOID LEUKEMIAS
INFECTIOUS DISEASES
POST-VIRAL INFLAMMATORY COMPLICATIONS​
LIVER DISEASES
FIBROSIS AND MASH/NASH ​
ANTI-INFLAMMATORY ADJUVANTS
CAR-T THERAPIES
OUR PARTNERS
SFA THERAPEUTICS
IS A
VENTURE CAPITAL BACKED CLINICAL-STAGE BIOTECHNOLOGY COMPANY









SFA THERAPEUTICS IN THE NEWS

JENKINTOWN, Pa., August 10, 2025 PR NEWSWIRE --The Galien Foundation Announces SFA Therapeutics as a 2025 Prix Galien USA Nominee for Best Startup
JENKINTOWN, Pa., May12, 2025 BIONJ -
SFA Therapeutics Awarded Most Innovative Company at BIONJ Liberty Center Partnering Conference
JENKINTOWN, Pa., April 28, 2025-- Pulse 2.0 SFA Therapeutics: Interview with CEO Dr. Ira Spector About the Biotech Company
JENKINTOWN, Pa., March 13, 2025 BioWorld -- First-in-class oral immunomodulator shows efficacy in psoriasis models​
JENKINTOWN, PA., March 13, 2025 --Technical.ly This pharma startup backed by Y Combinator aims to treat multiple diseases, for good
JENKINTOWN, Pa., March 7, 2025 BUSINESS WIRE -- SFA Therapeutics Announces Positive Phase 1b Data of SFA-002 in Mild-to-Moderate Psoriasis