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NEXT  GENERATION  DRUGS  TO  TREAT
AUTOIMMUNE,  CHRONIC   INFLAMMATORY   DISEASE
AND  CANCER

ABOUT SFA THERAPEUTICS

Our journey began with a deep fascination for the intricate world of the human gut bacterial ecosystem and its profound impact on overall well-being.  Our founders, a team of passionate researchers and healthcare professionals, were intrigued by the pivotal role this complex microbiota plays in maintaining human health.  The various bacteria produce a complex, yet synergistic, set of metabolites in our intestines that exhibit profound, wide-ranging effects on metabolism and immune function.

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​As we delved deeper into the science, we uncovered the potential of these biosynthetic molecules, that mimic naturally occurring substances, in addressing a variety of health challenges, from autoimmune disease to metabolic disorders. We were particularly captivated by how these simple organic compounds could influence complex cellular processes and serve as a communication bridge between our gut microbiome and immune system.

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We discovered ways of increasing the selectivity and specifictiy of our biosynthetics after elucidating pathways and targets.  We have developed a platform technology that allows us to target specific diseases and create disease-specific drugs.  â€‹â€‹â€‹â€‹Our technology platform represents a convergence of microbial science, pharmaceutical innovation, and precision medicine, offering new hope for patients across multiple therapeutic areas.  

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​Join us on this exciting journey as we work towards a healthier future, one molecule at a time.

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INNOVATIVE  DRUGS 

PREDICTABLE OUTCOMES

Innovative Oral   Formulations Allow for Consistent Clinical Outcomes

PATHWAY TARGETED

Small Molecules that Interact Selectively with Disease-specific Targets and Maintain Immune Homeostasis  

SUPERIOR 
SAFETY

Small Molecules that Mimic Endogenous Substances found in the Human Body
 

HIGHLY EFFICACIOUS

Boosts Anti-inlammatory IL-10 Expression and Downregulates Pro-inflammatory Cytokines

LOW COST

Seamless Manufacturing Process 

 POWERFUL  and  NOVEL  PLATFORM

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TARGETED BIOSYNTHESIS

PLATFORM

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AUTOIMMUNE DISEASES

PSORIASIS, RHEUMATOID ARTHRITIS,

UVEITIS AND BULLOUS PEMPHIGOID

CANCERS

HEPATOCELLULAR CARCINOMA, PANCREATIC CANCER AND MYELOID LEUKEMIAS

INFECTIOUS DISEASES

POST-VIRAL INFLAMMATORY COMPLICATIONS​

LIVER DISEASES

FIBROSIS AND MASH/NASH â€‹

ANTI-INFLAMMATORY ADJUVANTS

CAR-T THERAPIES

OUR PARTNERS

SFA THERAPEUTICS
IS  A

VENTURE  CAPITAL  BACKED  CLINICAL-STAGE  BIOTECHNOLOGY COMPANY

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SFA  THERAPEUTICS  IN  THE  NEWS

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JENKINTOWN, Pa., March 13, 2025  BioWorld -- First-in-class oral immunomodulator shows efficacy in psoriasis models​

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JENKINETOWN, PA., March 13, 2025 --Technical.ly This pharma startup backed by Y Combinator aims to treat multiple diseases, for good

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JENKINTOWN, Pa., March 7, 2025 BUSINESS WIRE -- SFA Therapeutics Announces Positive Phase 1b Data of SFA-002 in Mild-to-Moderate Psoriasis

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JENKINTOWN, Pa., March 7, 2025 PR NEWSWIRE -- Head-to-Head Preclinical Studies of SFA-002 as a Novel Psoriasis Treatment Presented at the 2025 American Academy of Dermatology Annual Meeting

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JENKINTOWN, Pa., January 15, 2025 Scrip -- Scrip Asks… What Does 2025 Hold For Biopharma? Part 2: Funding, M&A And Partnering - Early Stage Deals

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JENKINTOWN, Pa., January 5, 2025-- Philadelphia Inquirer New Scientific Discoveries Yield Impressive Real-World Applications

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